Which macromolecules are important in making cell membranes




















Carbohydrates provide energy to the body, particularly through glucose, a simple sugar that is a component of starch and an ingredient in many staple foods. Carbohydrates also have other important functions in humans, animals, and plants. This is because they are hydrocarbons that include mostly nonpolar carbon—carbon or carbon—hydrogen bonds. Lipids perform many different functions in a cell.

Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals.

It is found naturally in milk. Maltose, or malt sugar, is a disaccharide formed from a dehydration reaction between two glucose molecules. The most common disaccharide is sucrose, or table sugar, which is composed of the monomers glucose and fructose. The chain may be branched or unbranched, and it may contain different types of monosaccharides. Polysaccharides may be very large molecules.

Starch, glycogen, cellulose, and chitin are examples of polysaccharides. Starch is the stored form of sugars in plants and is made up of amylose and amylopectin both polymers of glucose. Plants are able to synthesize glucose, and the excess glucose is stored as starch in different plant parts, including roots and seeds. The starch that is consumed by animals is broken down into smaller molecules, such as glucose.

The cells can then absorb the glucose. Glycogen is the storage form of glucose in humans and other vertebrates, and is made up of monomers of glucose. Glycogen is the animal equivalent of starch and is a highly branched molecule usually stored in liver and muscle cells. Whenever glucose levels decrease, glycogen is broken down to release glucose. Cellulose is one of the most abundant natural biopolymers.

The cell walls of plants are mostly made of cellulose, which provides structural support to the cell. Wood and paper are mostly cellulosic in nature. Cellulose is made up of glucose monomers that are linked by bonds between particular carbon atoms in the glucose molecule. Every other glucose monomer in cellulose is flipped over and packed tightly as extended long chains. This gives cellulose its rigidity and high tensile strength—which is so important to plant cells.

Cellulose passing through our digestive system is called dietary fiber. While the glucose-glucose bonds in cellulose cannot be broken down by human digestive enzymes, herbivores such as cows, buffalos, and horses are able to digest grass that is rich in cellulose and use it as a food source.

In these animals, certain species of bacteria reside in the rumen part of the digestive system of herbivores and secrete the enzyme cellulase. The appendix also contains bacteria that break down cellulose, giving it an important role in the digestive systems of ruminants. Cellulases can break down cellulose into glucose monomers that can be used as an energy source by the animal. Carbohydrates serve other functions in different animals.

Arthropods, such as insects, spiders, and crabs, have an outer skeleton, called the exoskeleton, which protects their internal body parts. This exoskeleton is made of the biological macromolecule chitin , which is a nitrogenous carbohydrate.

It is made of repeating units of a modified sugar containing nitrogen. Thus, through differences in molecular structure, carbohydrates are able to serve the very different functions of energy storage starch and glycogen and structural support and protection cellulose and chitin. Registered Dietitian: Obesity is a worldwide health concern, and many diseases, such as diabetes and heart disease, are becoming more prevalent because of obesity.

This is one of the reasons why registered dietitians are increasingly sought after for advice. Registered dietitians help plan food and nutrition programs for individuals in various settings. They often work with patients in health-care facilities, designing nutrition plans to prevent and treat diseases.

For example, dietitians may teach a patient with diabetes how to manage blood-sugar levels by eating the correct types and amounts of carbohydrates. Dietitians may also work in nursing homes, schools, and private practices.

In addition, registered dietitians must complete a supervised internship program and pass a national exam. Those who pursue careers in dietetics take courses in nutrition, chemistry, biochemistry, biology, microbiology, and human physiology. Dietitians must become experts in the chemistry and functions of food proteins, carbohydrates, and fats. The underground storage bulb of the camas flower shown below has been an important food source for many of the Indigenous peoples of Vancouver Island and throughout the western area of North America.

Camas bulbs are still eaten as a traditional food source and the preparation of the camas bulbs relates to this text section about carbohydrates. Most often plants create starch as the stored form of carbohydrate. Some plants, like camas create inulin.

Inulin is used as dietary fibre however, it is not readily digested by humans. If you were to bite into a raw camas bulb it would taste bitter and has a gummy texture. The method used by Indigenous peoples to make camas both digestible and tasty is to bake the bulbs slowly for a long period in an underground firepit covered with specific leaves and soil. The heat acts like our pancreatic amylase enzyme and breaks down the long chains of inulin into digestible mono and di-saccharides.

Properly baked, the camas bulbs taste like a combination of baked pear and cooked fig. It is important to note that while the blue camas is a food source, it should not be confused with the white death camas, which is particularly toxic and deadly. The flowers look different, but the bulbs look very similar. Lipids include a diverse group of compounds that are united by a common feature. This is because they are hydrocarbons that include only nonpolar carbon-carbon or carbon-hydrogen bonds.

Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of lipids called fats. Lipids also provide insulation from the environment for plants and animals.

For example, they help keep aquatic birds and mammals dry because of their water-repelling nature. Lipids are also the building blocks of many hormones and are an important constituent of the plasma membrane. Lipids include fats, oils, waxes, phospholipids, and steroids. A fat molecule, such as a triglyceride, consists of two main components—glycerol and fatty acids.

Glycerol is an organic compound with three carbon atoms, five hydrogen atoms, and three hydroxyl —OH groups.

In a fat molecule, a fatty acid is attached to each of the three oxygen atoms in the —OH groups of the glycerol molecule with a covalent bond. During this covalent bond formation, three water molecules are released. The three fatty acids in the fat may be similar or dissimilar.

These fats are also called triglycerides because they have three fatty acids. Some fatty acids have common names that specify their origin. For example, palmitic acid, a saturated fatty acid, is derived from the palm tree. Arachidic acid is derived from Arachis hypogaea , the scientific name for peanuts. Fatty acids may be saturated or unsaturated.

In a fatty acid chain, if there are only single bonds between neighboring carbons in the hydrocarbon chain, the fatty acid is saturated. Saturated fatty acids are saturated with hydrogen; in other words, the number of hydrogen atoms attached to the carbon skeleton is maximized.

When the hydrocarbon chain contains a double bond, the fatty acid is an unsaturated fatty acid. Most unsaturated fats are liquid at room temperature and are called oils. If there is one double bond in the molecule, then it is known as a monounsaturated fat e. Saturated fats tend to get packed tightly and are solid at room temperature. Animal fats with stearic acid and palmitic acid contained in meat, and the fat with butyric acid contained in butter, are examples of saturated fats.

Mammals store fats in specialized cells called adipocytes, where globules of fat occupy most of the cell. In plants, fat or oil is stored in seeds and is used as a source of energy during embryonic development.

Unsaturated fats or oils are usually of plant origin and contain unsaturated fatty acids. Olive oil, corn oil, canola oil, and cod liver oil are examples of unsaturated fats.

Unsaturated fats help to improve blood cholesterol levels, whereas saturated fats contribute to plaque formation in the arteries, which increases the risk of a heart attack. In the food industry, oils are artificially hydrogenated to make them semi-solid, leading to less spoilage and increased shelf life.

Simply speaking, hydrogen gas is bubbled through oils to solidify them. During this hydrogenation process, double bonds of the cis -conformation in the hydrocarbon chain may be converted to double bonds in the trans -conformation. This forms a trans -fat from a cis -fat. The orientation of the double bonds affects the chemical properties of the fat.

Margarine, some types of peanut butter, and shortening are examples of artificially hydrogenated trans -fats. Many fast food restaurants have recently eliminated the use of trans -fats, and U. Essential fatty acids are fatty acids that are required but not synthesized by the human body. Consequently, they must be supplemented through the diet. Just as a hole in the wall can be a disaster for the castle, a rupture in the plasma membrane causes the cell to lyse and die.

The plasma membrane : The plasma membrane is composed of phospholipids and proteins that provide a barrier between the external environment and the cell, regulate the transportation of molecules across the membrane, and communicate with other cells via protein receptors. Among the most sophisticated functions of the plasma membrane is its ability to transmit signals via complex proteins. These proteins can be receptors, which work as receivers of extracellular inputs and as activators of intracellular processes, or markers, which allow cells to recognize each other.

Membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors, which then trigger intracellular responses. Some viruses, such as Human Immunodeficiency Virus HIV , can hijack these receptors to gain entry into the cells, causing infections. Membrane markers allow cells to recognize one another, which is vital for cellular signaling processes that influence tissue and organ formation during early development.

The fluid mosaic model describes the plasma membrane structure as a mosaic of phospholipids, cholesterol, proteins, and carbohydrates. The fluid mosaic model was first proposed by S. Singer and Garth L. Nicolson in to explain the structure of the plasma membrane. The model has evolved somewhat over time, but it still best accounts for the structure and functions of the plasma membrane as we now understand them.

The fluid mosaic model describes the structure of the plasma membrane as a mosaic of components —including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character. Plasma membranes range from 5 to 10 nm in thickness. The proportions of proteins, lipids, and carbohydrates in the plasma membrane vary with cell type. The Components and functions of the Plasma Membrane : The principal components of a plasma membrane are lipids phospholipids and cholesterol , proteins, and carbohydrates attached to some of the lipids and some of the proteins.

The fluid mosaic model of the plasma membrane : The fluid mosaic model of the plasma membrane describes the plasma membrane as a fluid combination of phospholipids, cholesterol, and proteins. Carbohydrates attached to lipids glycolipids and to proteins glycoproteins extend from the outward-facing surface of the membrane.

The main fabric of the membrane is composed of amphiphilic or dual-loving, phospholipid molecules. The hydrophilic or water-loving areas of these molecules are in contact with the aqueous fluid both inside and outside the cell.

Hydrophobic, or water-hating molecules, tend to be non- polar. A phospholipid molecule consists of a three-carbon glycerol backbone with two fatty acid molecules attached to carbons 1 and 2, and a phosphate-containing group attached to the third carbon. This arrangement gives the overall molecule an area described as its head the phosphate-containing group , which has a polar character or negative charge, and an area called the tail the fatty acids , which has no charge.

They interact with other non-polar molecules in chemical reactions, but generally do not interact with polar molecules. When placed in water, hydrophobic molecules tend to form a ball or cluster.

The hydrophilic regions of the phospholipids tend to form hydrogen bonds with water and other polar molecules on both the exterior and interior of the cell. Thus, the membrane surfaces that face the interior and exterior of the cell are hydrophilic. In contrast, the middle of the cell membrane is hydrophobic and will not interact with water. Therefore, phospholipids form an excellent lipid bilayer cell membrane that separates fluid within the cell from the fluid outside of the cell.

Phospholipid aggregation : In an aqueous solution, phospholipids tend to arrange themselves with their polar heads facing outward and their hydrophobic tails facing inward. The structure of a phospholipid molecule : This phospholipid molecule is composed of a hydrophilic head and two hydrophobic tails.

The hydrophilic head group consists of a phosphate-containing group attached to a glycerol molecule. The hydrophobic tails, each containing either a saturated or an unsaturated fatty acid, are long hydrocarbon chains. Proteins make up the second major component of plasma membranes.



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