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Download references. We thank J. Thompson for providing IF2 strains, M. Schultz, D. Moras, J. Thierry, V. Mallouh, G. Yusupova and I. Orlov for their constant support and interest. Descartes, Strasbourg, France. You can also search for this author in PubMed Google Scholar. Correspondence to Bruno P. PDF kb. Reprints and Permissions. Structure of the 30S translation initiation complex. Download citation. Received : 20 February Accepted : 23 June Published : 31 August Issue Date : 18 September Anyone you share the following link with will be able to read this content:.
Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. Nature Communications Choose the membership that is right for you. Discount will be applied automatically at checkout. Your account has been created successfully, and a confirmation email is on the way. Credit: Science Structure of the bacterial transcription initiation complex formed by RNA polymerase gray , the transcription initiation factor sigma yellow , and promoter DNA dark blue, light blue, pink, and red.
A high-resolution structure of the transcription initiation complex formed by RNA polymerase, an initiation factor, and a gene promoter helps elucidate how DNA is recognized, unwound, and prepared for transcription to RNA Science, DOI: The structure of the bacterial complex could facilitate the development of new antibacterial agents and aid understanding of transcription in higher organisms, which is structurally and mechanistically similar. The structure, obtained by Richard H.
Ebright , Eddy Arnold , and coworkers at Rutgers University, includes parts of the complex never before determined at high resolution. Contact the reporter. Submit a Letter to the Editor for publication. Engage with us on Twitter. The power is now in your nitrile gloved hands Sign up for a free account to increase your articles. Or go unlimited with ACS membership.
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