Natural Medicines Comprehensive Database. Stockton, Calif. Pharmacological activities of Vitex agnus-castus extracts in vitro. In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus castus: direct evidence for a dopaminergic principle by the dopamine receptor assay.
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Roseville, Calif. McGuffin M. Boca Raton, Fla. Shuster J. Black cohosh root? Chasteberry tree? Hospital Pharmacy. This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference.
Forty drops of the concentrated liquid herbal extract of vitex can be added to a glass of water and drunk in the morning. Vitex is also available in powdered form in tablets and capsules. Thirty-five to forty milligrams may be taken in the morning. Numerous herbs, known as galactagogues, are used in traditional herbal medicine systems around the world to promote production of breast milk. These are known as galactagogues.
Vitex is one of the best recognized herbs in Europe for promoting lactation. An older German clinical trial found that 15 drops of a vitex tincture three times per day could increase the amount of milk produced by mothers with or without pregnancy complications, as compared with mothers given vitamin B1 or nothing. However, vitex should not be taken during pregnancy.
Hippocrates, Dioscorides, and Theophrastus mention the use of vitex for a wide variety of conditions, including hemorrhage following childbirth and assisting with the "passing of afterbirth.
In addition, vitex was believed to suppress libido and inspire chastity, which explains one of its common names, chaste tree.
Vitex contains several different constituents, including flavonoids, iridoid glycosides, and terpenoids. The whole fruit extract, rather than one of its individual constituents, appears to be necessary for the medicinal activity of vitex. The benefits of vitex stem from its actions upon the pituitary gland—specifically on the production of a hormone called luteinizing hormone LH.
This indirectly increases progesterone production and helps regulate the menstrual cycle. Vitex also keeps prolactin secretion in check.
A controlled clinical trial found that women taking 20 mg per day of a concentrated vitex extract for three menstrual cycles had a significant reduction in symptoms of PMS, including irritability, mood swings, headache, and breast tenderness.
A review of other trials and case reports suggests there is at least preliminary support that vitex should be considered for women with irregular periods, infertility, and mildly elevated prolactin levels.
Caution: Agnus castus should not be taken during pregnancy. The German Commission E monograph recommends a daily intake—30—40 mg of the dried herb—in capsules or in liquid preparations. With its emphasis on long-term balancing of a woman's hormonal system, vitex is not a fast-acting herb and is unlikely to give immediate relief to the discomfort associated with PMS. For premenstrual syndrome , frequent or heavy periods, vitex can be used continuously for four to six months.
Infertile women with amenorrhea lack of menstruation can remain on vitex for 12 to 18 months, unless pregnancy occurs during treatment. Side effects may include minor stomach upset and a mild skin rash with itching. Vitex is not recommended for use during pregnancy and should not be used concurrently with hormone therapy e.
Agnus castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res ; The use of Vitex agnus castus for hyperprolactinemia. Quart Rev Nat Med ;Spring Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomized, placebo controlled study.
BMJ ; Treatment of premenstrual tension syndrome with Vitex agnus-castus. Controlled, double-blind study versus pyridoxine. Phytomedicine ; Premenstrual syndrome: Treatment with a phytopharmaceutical. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. Treatment of cyclical mastalgia with a solution containing Vitex agnus extract: results of a placebo-controlled double-blind study.
The Breast ; Bone K. Vitex agnus-castus: Scientific studies and clinical applications. Eur J Herbal Med ; Vitex agnus castus extract for the treatment of menstrual irregularities due to latent hyperprolactinemia. Arzneim Forsch ; [in German]. Amann W. Improvement of acne vulgaris following therapy with Agnus castus Agnolyt.
Ther Ggw ; [in German]. Learn more about TraceGains, the company. The information presented by TraceGains is for informational purposes only. It is based on scientific studies human, animal, or in vitro , clinical experience, or traditional usage as cited in each article.
The results reported may not necessarily occur in all individuals. J Altern Complement Med. Double-blind, placebo-controlled study of Fertilityblend: a nutritional supplement for improving fertility in women. Clin Exp Obstet Gynecol. Vitex agnus castus: a systematic review of adverse events.
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Table of Contents. What Is Vitex Used For? Possible Side Effects. Dosage and Preparation. What to Look For. Frequently Asked Questions What is a chaste tree? What are the benefits of chasteberry?
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